斯德哥爾摩大學(xué)Per E. M. Siegbahn教授做客第210期化苑講壇

報(bào)告題目：Methods and models for investigating mechanisms of redox-active enzymes

報(bào) 告 人：Per E. M. Siegbahn（國(guó)際量子分子科學(xué)院院士，瑞典皇家科學(xué)院院士，諾貝爾獎(jiǎng)評(píng)委，斯德哥爾摩大學(xué)教授）

報(bào)告時(shí)間：2016年10月9日上午10：00

報(bào)告地點(diǎn)：化學(xué)樓二樓一號(hào)會(huì)議室

報(bào)告人簡(jiǎn)介：

Prof. Per E. M. Siegbahn was born in Stockholm, Sweden. He did his undergraduate studies at Uppsala University and received his Ph.D. degree at Stockholm University in 1973 (with Bjorn Roos). He was a postdoctoral fellow at the University of California, Berkeley (with Henry F. Schaefer, III), and at IBM, San Jose (with Bowen Liu). He returned to Stockholm and has remained ever since. He has published over 300 papers in international journals, including Chem. Rev., Acc. Chem. Res., Proc. Natl. Acad. Sci. U.S.A., Angew. Chem. Int. Ed., and J. Am. Chem. Soc.

報(bào)告內(nèi)容：

Methods and models have been developed during the past twenty years that are capable of solving mechanistic questions for redox-active enzymes. The strategy adapted has been to base all conclusions on experience, without pre-assumptions. A very large number of model calculations were performed to test the strategy chosen, by far more than by any other group in this area of quantum chemistry. Some of the most difficult problems in biochemistry has by now been solved, most notable the one of water oxidation in Photosystem II. But for many other enzymes the calculations have given mechanisms, never suggested before, which only later on have been confirmed by experiments.