報告題目：Pushing the Limits of Coordination-Driven Self-Assembly: Construction of Giant 2D and 3D Supramolecular Architectures
報告人：Prof. Xiaopeng Li (李霄鵬教授)
University of South Florida
報告時間：2019年12月4日（周三）下午3:00-5:00
報告地點：化學(xué)樓一號會議室
邀請人：朱錦濤 教授
報告人簡介
李霄鵬教授2004 年于鄭州大學(xué)化學(xué)系獲本科學(xué)位，2008 年在美國克利夫蘭州立大化學(xué)系獲博士學(xué)位。2009 起在阿克倫大學(xué)從事博士后研究。2012 年在德州州立大學(xué)任化學(xué)系助理教授，開展獨立工作。2016 年至今在南佛羅里達(dá)大學(xué)先后任助理教授、副教授。主要研究興趣集中用超分子化學(xué)以及質(zhì)譜表征技術(shù)。曾獲得多個獎項，包括超分子領(lǐng)域著名的Cram Lehn Pedersen Prize(2019)、英國皇家化學(xué)會Fellow (FRSC, 2017)、中美華人化學(xué)與化學(xué)生物學(xué)教授協(xié)會杰出青年教授獎(CAPA，2017)、德州州立大學(xué)杰出學(xué)術(shù)成就獎(2016)、美國Research Corporation 基金會 Cottrell 學(xué)者獎 (2015)。共發(fā)表150 余篇論文，文章總引用次數(shù)超過5000 次，H-index 42。
報告摘要
Due to its highly directional and predictable feature, coordination-driven self-assembly has evolved into a well-established methodology for constructing 2D and 3D supramolecules. Up to date, this field has matured in the context of a large variety of macrocycles and polyhedra, which however, still suffered from a lack of complexity and thus were unable to reach the high degrees of functionality found in natural systems. With the goal of assembling structures with high complexity, we pushed the limits of coordination self-assembly through constructing a series of giant 2D and 3D supramolecular architectures. First, multi-armed building blocks were synthesized using pyrylium and pyridinium salts chemistry for the self-assembly of 2D nested concentric hexagons, or Kandinsky circles, which showed high antimicrobial activity. Second, step-wise strategy was utilized to combine folding and self-assembly together to construct fuzzy supramolecular hexagonal grids (diameter > 20 nm, MW > 65 kDa) with intrinsically ordered and disordered domains. Third, pre-assembled supramolecular polyhedra with precisely-controlled shapes and sizes could further assemble into double-helical nanowires with a non-natural parastichy pattern. In conclusion, through further understanding of self-assembly of supramolecules, our research could advance the design, research and development of new synthetic materials with molecular level precision.
